Surface Antigen Loss & Transaminase Flares – Critical Milestones for Achieving Functional Cure

Time: 9:00 am
day: Day Two


• Understand how a surface antigen (subviral particles) is produced independently from viral replication and blocks restoration of immune function

• Discuss why surface antigen clearance is required for efficient targeting of infected hepatocytes

• Demonstrate how transaminase flares signal recovery of immune function and removal of hepatocytes containing integrated HBV DNA – a critical event for functional cure